Streptococcal Pneumonia for Neutrophil Extravasation During Role of Galectin-3 as an Adhesion Molecule
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Targeting CD162 protects against streptococcal M1 protein-evoked neutrophil recruitment and lung injury.
Streptococcus pyogenes of the M1 serotype can cause streptococcal toxic shock syndrome and acute lung damage. CD162 is an adhesion molecule that has been reported to mediate neutrophil recruitment in acute inflammatory reactions. In this study, the purpose was to investigate the role of CD162 in M1 protein-provoked lung injury. Male C57BL/6 mice were treated with monoclonal antibody directed ag...
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تاریخ انتشار 2002